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Updated: Jun 3, 2026

Development of Obliterative Bronchiolitis in a Murine Model of Orthotopic Lung Transplantation
Published on: July 10, 2012
Pneumothorax derived from bronchiolitis obliterans after marrow transplantation
Sumitaka Yamanaka1, Taketsugu Yamamoto, Kenji Inui
1Department of Thoracic Surgery, Yokohama City University Medical Center, Yokohama, Japan. syamana1@jhmi.edu
Abstract:
Long-term survival has become achievable after bone-marrow transplantation, but various pulmonary diseases due to chronic graft-vs.-host disease have been recognized. Particularly, bronchiolitis obliterans is a life-threatening complication with no effective remedy. Bilateral pneumothorax associated with bronchiolitis obliterans is rare, but it requires careful attention. In a 42-year old man with intractable pneumothorax after bone marrow transplantation and surgical procedures, extensive thoracolysis was effective as an acute treatment for this disease.
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