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Peptide toxin components of Amanita exitialis basidiocarps
Wang-Qiu Deng1, Tai-Hui Li, Ping-Gen Xi
1Guangdong Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangdong Guangzhou, China.
Abstract:
Eight peptide toxins were isolated and purified from basidiocarps of Amanita exitialis with high performance liquid chromatography and were subjected to ultraviolet, nuclear magnetic resonance and mass spectrometry. We identified seven peptide toxins, α-amanitin, β-amanitin, amaninamide, phallacin, phallacidin, phallisacin and desoxoviroidin. The molecular weight (729.5 Da) of the eighth compound did not match that of any reported Amanita toxins and, although the UV absorption spectrum indicated it to be a phallotoxin, further studies are required to identify this component. This is the first report of amaninamide, phallacin, phallisacin and desoxoviroidin in this lethal mushroom species.
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