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Low level laser therapy in oral mucositis: a pilot study.
1Dept of Paediatric Dentistry, University Hospital, De Pintelaan 158, B 9000 Ghent, Belgium. rita.cauwels@ugent.be
Summary
Low level laser therapy (LLLT) effectively relieved pain and accelerated wound healing in children with chemotherapy-induced oral mucositis (OM). This promising treatment reduced OM severity and duration, offering significant pain relief and functional improvement.
Area of Science:
- Oncology
- Laser Therapy
- Oral Medicine
Background:
- Chemotherapy-induced oral mucositis (OM) is a common, painful side effect in pediatric oncology.
- Current treatments for OM have limited efficacy and can cause side effects.
Observation:
- A pilot study evaluated low level laser therapy (LLLT) for OM in 16 pediatric oncology patients.
- Patients received GaAlAs diode laser (830 nm) treatment every 48 hours, with energy adjusted to OM severity (WHO classification).
- Pain, functional impairment, and wound healing were monitored before and after treatment.
Findings:
- LLLT provided immediate pain relief after each session.
- An average of 2.5 treatments within one week healed OM lesions.
- All patients experienced improved wound healing and resolved functional impairment.
Implications:
- LLLT, specifically with a GaAlAs 830nm diode laser, shows significant potential for managing pediatric OM.
- This therapy can reduce OM severity, duration, and pain, improving patient comfort and quality of life.
- New treatment guidelines for LLLT in OM could be developed based on WHO-OM grades and energy levels.
