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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures ll: Types01:19

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...
Alterations in Muscle Tone ll01:12

Alterations in Muscle Tone ll

Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...

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Related Experiment Video

Updated: Jun 3, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
09:32

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients

Published on: December 18, 2016

Drug-resistant temporal lobe epilepsy is associated with postural control abnormalities.

S Colnat-Coulbois1, G C Gauchard, L Maillard

  • 1Balance Control and Motor Performance, UFR STAPS, Henri Poincaré University Nancy I, Villers-lès-Nancy, France. s.coulbois@chu-nancy.fr

Epilepsy & Behavior : E&B
|April 9, 2011
PubMed
Summary

Patients with epilepsy, particularly temporal lobe epilepsy (TLE), exhibit impaired postural control, especially when relying on vestibular input. This suggests vestibular dysfunction contributes to falls in TLE patients.

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Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
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Last Updated: Jun 3, 2026

Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
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Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study
11:29

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Area of Science:

  • Neurology
  • Vestibular System Function
  • Balance Disorders

Background:

  • Falls in epilepsy are common, often occurring without seizures, indicating potential postural control deficits.
  • Limited research exists on postural control in epilepsy, with no studies specifically examining temporal lobe epilepsy (TLE).
  • The temporal cortex, housing vestibular areas, is implicated in TLE, suggesting a potential link to balance issues.

Purpose of the Study:

  • To investigate postural control characteristics in patients with complex partial temporal lobe epilepsy (TLE).
  • To compare postural control between TLE patients and age-matched healthy controls.

Main Methods:

  • A homogeneous group of 26 TLE patients and 26 healthy controls participated.
  • Participants underwent a Sensory Organization Test (SOT) with six conditions.
  • The SOT evaluated balance under normal and sensory-conflicting situations, including altered visual, somatosensory, and vestibular inputs.

Main Results:

  • Patients with TLE demonstrated significantly poorer postural control compared to healthy controls.
  • The deficit was most pronounced in conditions requiring vestibular information for balance.
  • This suggests vestibular dysfunction plays a role in postural instability in TLE.

Conclusions:

  • Postural control is impaired in patients with complex partial TLE.
  • Vestibular dysfunction, potentially linked to temporal lobe pathology or antiepileptic drug side effects, may underlie falls in TLE.
  • Findings enhance understanding of fall mechanisms in epilepsy and highlight the importance of vestibular assessment.