Related Experiment Video
Updated: Jun 3, 2026

A Mouse Model of Orthopedic Surgery to Study Postoperative Cognitive Dysfunction and Tissue Regeneration
Published on: February 27, 2018
Review articles: postoperative delirium: acute change with long-term implications
James L Rudolph1, Edward R Marcantonio
1Geriatric Research, Education, and Clinical Center, VA Boston Healthcare System GRECC, 150 South Huntington Ave., Boston, MA 02130, USA. jrudolph@partners.org
Postoperative delirium, an acute cognitive change, impacts older patients most. Early risk assessment, prevention, and standardized treatment are crucial for better surgical recovery and reduced hospital costs.
Area of Science:
- Geriatrics
- Neuroscience
- Anesthesiology
Background:
- Delirium is an acute change in cognition and attention, often affecting older patients, particularly those with pre-existing cognitive impairment.
- Postoperative delirium is linked to slower recovery, extended hospital stays, and increased healthcare costs.
- Its incidence varies based on surgical factors and assessment methods.
Purpose of the Study:
- To provide a comprehensive guide for assessing, preventing, diagnosing, and treating delirium in the perioperative setting.
- To highlight the importance of early risk identification and proactive management strategies.
Main Methods:
- Review and synthesis of current literature on delirium assessment and management.
- Emphasis on preoperative risk stratification and implementation of evidence-based prevention programs.
- Development of standardized treatment protocols for postoperative delirium.
Main Results:
- Delirium can persist long-term, leading to poor cognitive and functional outcomes.
- Care improvements, including preoperative risk identification and staff training, can mitigate delirium incidence.
- Standardized protocols and prevention programs are effective in reducing delirium-associated morbidity.
Conclusions:
- Proactive perioperative care, including risk assessment and targeted interventions, is essential for managing delirium.
- Implementing structured programs for delirium prevention and treatment can significantly improve patient outcomes and reduce healthcare burdens.
- Multidisciplinary collaboration is key to effectively addressing postoperative delirium.
Related Concept Videos
Long-term Depression
Calcium Ion Concentration Mechanism
If over time, all...
Long-term Depression
Stages of General Anesthesia
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Peripheral Artery Disease V: Postoperative Nursing Management
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...