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Varicose Veins I: Introduction

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Related Experiment Video

Updated: Jun 2, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

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Varicose veins.

¹Bedford Hospital, Bedford, UK.

BMJ Clinical Evidence

|April 12, 2011

Summary

This summary is machine-generated.

This systematic review evaluates treatments for varicose veins, finding various interventions like compression stockings, laser therapy, and surgery effective. Evidence quality was assessed using GRADE to inform treatment choices for this common condition.

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Area of Science:

Vascular Medicine
Phlebology

Background:

Varicose veins result from venous valve dysfunction and reduced vein wall elasticity, leading to blood pooling and vein enlargement.
Affecting up to 40% of adults, varicose veins are more prevalent in obese individuals and women with multiple pregnancies.

Purpose of the Study:

To systematically review the effects of various treatments for varicose veins in adults.
To assess the effectiveness and safety of different therapeutic interventions.

Main Methods:

A systematic review was conducted, searching major databases (Medline, Embase, Cochrane Library) up to January 2010.
Included studies comprised systematic reviews, randomized controlled trials (RCTs), and observational studies.
Harms alerts from regulatory agencies (FDA, MHRA) were also incorporated.

Main Results:

A total of 39 studies met the inclusion criteria for the review.
The GRADE system was utilized to evaluate the quality of evidence for each intervention.

Conclusions:

The review presents data on the effectiveness and safety of interventions including compression stockings, endovenous laser, injection sclerotherapy, radiofrequency ablation, self-help strategies, and surgical options.
Information is provided for treatments such as stripping, avulsion, and powered phlebectomy.