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Updated: Jun 2, 2026

Glass-Based Devices to Generate Drops and Emulsions
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Controlled drop emission by wetting properties in driven liquid filaments.

R Ledesma-Aguilar1, R Nistal, A Hernández-Machado

  • 1Departament d'Estructura i Constituents de la Matèria, Universitat de Barcelona, Avinguda Diagonal 647, E-08028 Barcelona, Spain. ra.ledesma@gmail.com

Nature Materials
|April 12, 2011
PubMed
Summary

Researchers discovered a new way to create tiny droplets using a wetting-based mechanism. This method allows for controlled droplet size and emission, paving the way for advanced microfluidic applications.

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Area of Science:

  • Fluid dynamics
  • Surface science
  • Microfluidics

Background:

  • Controlled formation of micrometer-sized drops is crucial for various technological applications.
  • Existing methods for droplet generation often lack precise control over size and emission frequency.

Purpose of the Study:

  • To present a novel wetting-based destabilization mechanism for controlled droplet emission.
  • To investigate the critical parameters influencing droplet formation in microfilaments.

Main Methods:

  • Analysis of a wetting-based destabilization mechanism in forced microfilaments on patterned substrates (hydrophilic/hydrophobic stripes).
  • Theoretical prediction of critical filament velocity as a function of static wetting angle and filament size.
  • Experimental validation of the mechanism and its control capabilities.

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Generation of Size-controlled Poly (ethylene Glycol) Diacrylate Droplets via Semi-3-Dimensional Flow Focusing Microfluidic Devices
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Fabricating High-viscosity Droplets using Microfluidic Capillary Device with Phase-inversion Co-flow Structure
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Main Results:

  • A periodic droplet emission mechanism was identified, triggered above a critical forcing threshold.
  • The critical filament velocity is dependent on the static wetting angle and filament size, explaining differences between hydrophilic and hydrophobic surfaces.
  • Independent control over droplet size and emission period was demonstrated.

Conclusions:

  • The presented mechanism offers a new approach for producing highly monodisperse and flexible droplets.
  • This technique has potential applications in open microfluidic geometries for precise material deposition and manipulation.