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Related Concept Videos

Anorexia Nervosa01:28

Anorexia Nervosa

Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
Bulimia Nervosa01:30

Bulimia Nervosa

Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
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Panic Disorder

Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...

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Assessing Activity-based Anorexia in Mice
08:26

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Published on: May 14, 2018

Anorexia nervosa.

Kathleen Kara Fitzpatrick1, James Lock

  • 1Stanford University, Stanford, USA.

BMJ Clinical Evidence
|April 13, 2011
PubMed
Summary
This summary is machine-generated.

This systematic review evaluates treatments for anorexia nervosa, a serious eating disorder. It examines interventions for the condition and its complications, providing evidence on effectiveness and safety.

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Using the Activity-based Anorexia Rodent Model to Study the Neurobiological Basis of Anorexia Nervosa

Published on: October 22, 2015

Area of Science:

  • Eating Disorders
  • Clinical Psychology
  • Pharmacology

Background:

  • Anorexia nervosa is a severe eating disorder characterized by low BMI, fear of weight gain, and health denial.
  • Prevalence is highest in teenage girls, with significant mortality and chronicity rates.
  • Affected individuals face increased risks of bone fractures and long-term health complications.

Purpose of the Study:

  • To systematically review the effects of treatments for anorexia nervosa.
  • To evaluate interventions aimed at preventing or treating anorexia nervosa complications.
  • To assess the safety and effectiveness of various therapeutic approaches.

Main Methods:

  • Systematic review of 40 studies including systematic reviews, RCTs, and observational studies.
  • Searched major databases (Medline, Embase, Cochrane Library) up to April 2010.
  • Included harms alerts from regulatory agencies (FDA, MHRA) and applied GRADE evaluation.

Main Results:

  • Identified studies evaluating atypical antipsychotics, benzodiazepines, cyproheptadine, and older antipsychotics.
  • Assessed inpatient/outpatient settings, hormone replacement therapy (HRT), oral contraceptives, psychotherapy, refeeding, SSRIs, and tricyclic antidepressants.
  • Evaluated the quality of evidence for various interventions using GRADE methodology.

Conclusions:

  • The review presents data on the effectiveness and safety of diverse anorexia nervosa interventions.
  • Information covers pharmacological and psychological treatments, as well as nutritional rehabilitation.
  • Evidence synthesis aids in understanding treatment options for anorexia nervosa and its associated risks.