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Updated: Jun 2, 2026

In Vivo Imaging Systems (IVIS) Detection of a Neuro-Invasive Encephalitic Virus
Published on: December 2, 2012
[Infectious ventriculitis in relation with neurocysticercosis in Burkina Faso]
1UFR sciences de la santé, service de neurologie, CHU Yalgado Ouédraogo 03, BP 7022, Ouagadougou 03, Burkina Faso. naponc@yahoo.fr
Introduction:
Ventriculitis is an uncommon entity, which is defined as localized meningitis in the cerebral ventricles. It usually occurs in a context of immunodepression, where its presence may suggest primary brain lymphoma, certain viral infections including cytomegalovirus (CMV) and much more rarely, tuberculous meningitis.
Observation:
A 48-year-old immunocompetent male was admitted to the neurology department of the Ouagadougou teaching hospital with the diagnosis of infectious ventriculitis in relation with neurocysticercosis (NCC). The diagnosis was based on several arguments including brain CT scan (dilated lateral and third ventricles with ependymal enhancement and scattered parenchymatous cystic hypodensities exhibiting enhancement after contrast injection), the notion of exposure (the patient raised pigs), residence in an endemic zone of cysticercosis, and test results: CSF analysis (aseptic meningitis), positive ELISA for NCC in both CSF and blood. The good clinical and biological outcome after treatment with albendazole was another argument favoring the diagnosis.
Conclusion:
This illustrates the importance of searching for NCC in patients with ventriculitis residing in an endemic zone for cysticercosis.
Insights
Neurocysticercosis (NCC) can cause infectious ventriculitis in immunocompetent individuals. Early diagnosis and treatment with albendazole are crucial for favorable outcomes in endemic areas.
Area of Science:
- Neurology
- Infectious Diseases
- Parasitology
Background:
- Ventriculitis, localized meningitis in cerebral ventricles, is rare.
- Often associated with immunosuppression, suggesting lymphoma, CMV, or tuberculous meningitis.
Observation:
- An immunocompetent 48-year-old male presented with infectious ventriculitis.
- Diagnosis involved neuroimaging (CT scan), exposure history (pig farming), endemic residence, and positive ELISA for NCC in CSF and blood.
- Aseptic meningitis was noted in CSF analysis.
Findings:
- Neurocysticercosis (NCC) was identified as the cause of ventriculitis.
- Treatment with albendazole led to good clinical and biological recovery.
Implications:
- Highlights the importance of considering NCC in ventriculitis cases within cysticercosis-endemic regions.
- Emphasizes the need for targeted diagnostic workups in at-risk populations.
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Brain Abscess l: Introduction
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Encephalitis l: Introduction
Encephalitis ll: Pathophysiology

