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Development of tolerance to the ACTH-releasing effects of beta-endorphin
Research Communications in Chemical Pathology and Pharmacology
|October 1, 1978
Abstract:
Acute intracisternal injection of human beta-endorphin results in increased plasma concentration of adrenocorticotropic hormone (ACTH). Repeated injections of beta-endorphin are associated with the development of tolerance with regard to this ACTH-stimulating effect.