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Abnormal embryonic heart rate pattern in early pregnancy associated with Down's syndrome
R Schats1, C A Jansen, J W Wladimiroff
1Department of Obstetrics and Gynaecology/IVF, Diaconessenhuis, Voorburg, The Netherlands.
Human Reproduction (Oxford, England)
|October 1, 1990
Abstract:
The case history of a 35-year-old woman with a pregnancy following IVF treatment is presented. Transvaginal sonography revealed an abnormal pattern of the embryonic heart rate between 28 and 50 days following follicular aspiration. At term, a male infant with the characteristics of Down's syndrome was born. The diagnosis was confirmed by chromosome analysis. The implications of this observation are discussed.