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Updated: Jun 2, 2026

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Gene-therapy Inspired Polycation Coating for Protection of DNA Origami Nanostructures
Published on: January 19, 2019
A supramolecular approach to the preparation of charge-tunable dendritic polycations for efficient gene delivery
Ruijiao Dong1, Linzhu Zhou, Jieli Wu
1School of Chemistry and Chemical Engineering, State Key Laboratory of Metal Matrix Composites, Shanghai Jiao Tong University, 800 Dongchuan Road, 200240 Shanghai, People's Republic of China.
Abstract:
A facile supramolecular approach for the preparation of charge-tunable dendritic polycations, by a combination of the multi-functionality of dendritic polymers with the dynamic-tunable ability of supramolecular polymers, has been developed. It provides a new strategy for designing and developing efficient gene vectors via noncovalent interactions.

