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A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
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Diagnostic accuracy of dual-source CT coronary angiography with prospective ECG-triggering on different heart rate

Ming-Li Sun1, Bin Lu, Run-Ze Wu

  • 1Department of Radiology, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, #167 Bei-Li-Shi Street, Beijing 100037, China.

European Radiology
|April 13, 2011
PubMed

Insights

Dual-source CT coronary angiography with prospective ECG-triggering demonstrates high diagnostic accuracy across various heart rates (HR). This technique is reliable for detecting coronary artery disease, even in patients with medium to high HR.

Area of Science:

  • Cardiovascular Imaging
  • Radiology
  • Medical Diagnostics

Background:

  • Dual-source CT (DSCT) prospective ECG-triggering coronary angiography is a non-invasive imaging technique.
  • Assessing its diagnostic accuracy across different patient heart rates (HR) is crucial for clinical application.

Purpose of the Study:

  • To evaluate the diagnostic accuracy of DSCT prospective ECG-triggering coronary angiography.
  • To compare accuracy in patients with low, medium, and high heart rates.

Main Methods:

  • 103 patients with suspected coronary artery disease underwent DSCT and invasive coronary angiography (ICA).
  • Patients were grouped by HR: low (≤60 bpm), medium (60-70 bpm), and high (>70 bpm).
  • Sensitivity and specificity for detecting ≥50% stenosis were compared; ICA served as the gold standard.

Main Results:

  • DSCT showed high sensitivity and specificity across all HR groups (e.g., 82.8% and 98.4% in low HR; 88.3% and 98.7% in medium HR; 80.3% and 98.6% in high HR).
  • No significant differences in diagnostic accuracy were found between HR subgroups (p > 0.05).
  • Image quality scores were consistently high (around 3.1/4.0) across groups, with an average effective radiation dose of 3.60 mSv.

Conclusions:

  • DSCT prospective ECG-triggering coronary angiography is accurate for diagnosing coronary artery disease regardless of patient heart rate.
  • The technique performs comparably in patients with low, medium, and high heart rates.
  • This supports its use in a broad patient population.
Abstract

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