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Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography

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Relationship between peripheral blood flow in extremities and choroidal circulation.

A Polunina¹, K Gugleta, A Kochkorov

¹Ophthalmology Department, University Hospital Basel, Basel, Switzerland.

Klinische Monatsblatter Fur Augenheilkunde

|April 13, 2011

Summary

Individuals with colder extremities, both subjectively and objectively measured, exhibit higher choroidal blood flow (CBF). This suggests a potential redistribution of blood flow in response to cold extremities.

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Area of Science:

Ophthalmology
Physiology
Medical Research

Background:

Investigating the link between peripheral temperature and ocular circulation.
Understanding physiological responses to cold extremities.

Purpose of the Study:

To determine the relationship between finger temperature and choroidal blood flow (CBF).
To assess if subjective reports of cold extremities correlate with objective measurements and CBF.

Main Methods:

Submacular choroidal blood flow (CBF) was measured in 73 healthy subjects.
Subjects were grouped based on self-reported frequency of cold extremities.
Finger temperature was objectively measured using an infrared thermometer (IRT).

Main Results:

A statistically significant difference in CBF was observed between groups (ANOVA p=0.04).
A significant negative correlation was found between CBF and IRT measurements (Pearson's R = -0.51, p < 0.001).
Higher frequency of cold extremities was associated with higher CBF.

Conclusions:

Both subjective and objective measures of colder extremities correlate with increased choroidal blood flow.
This association may indicate a blood flow redistribution mechanism in response to peripheral coldness.