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Electrocardiographic abnormalities in tropical pulmonary eosinophilia
S K Agarwal1, D C Roy, A Johri
1Department of Chest Diseases, Banaras Hindu University, Varanasi.
The Indian Journal of Chest Diseases & Allied Sciences
|January 1, 1990
Summary
Electrocardiogram abnormalities are common in tropical pulmonary eosinophilia, with most cases resolving after diethylcarbamazine treatment. This study highlights the impact of this parasitic infection on cardiac electrical activity.
Area of Science:
- Cardiology
- Infectious Diseases
- Pulmonology
Background:
- Tropical pulmonary eosinophilia (TPE) is a parasitic lung disease.
- Cardiac involvement in TPE is not well-documented.
Purpose of the Study:
- To investigate electrocardiogram (ECG) abnormalities in patients with TPE.
- To assess the effect of diethylcarbamazine (DEC) therapy on these ECG changes.
Main Methods:
- A 12-lead ECG was performed on 70 patients diagnosed with TPE.
- Patients received DEC at a dose of 10 mg/kg body weight for 14 days.
- Post-treatment ECGs were compared to baseline findings.
Main Results:
- 28.57% of patients exhibited ECG abnormalities.
- Common findings included right axis deviation, 'P' pulmonale, and ST-T changes.
- All observed ECG abnormalities normalized after DEC treatment.
Conclusions:
- ECG abnormalities are present in a significant portion of TPE patients.
- DEC therapy effectively reverses cardiac electrical changes associated with TPE.
- ECG monitoring may be useful in managing TPE patients.