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Updated: Jun 2, 2026

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

Published on: January 21, 2018

Bronchiolitis.

Thomas Bourke¹, Michael Shields

¹Emergency Department, Royal Belfast Hospital for Sick Children, Belfast, UK.

BMJ Clinical Evidence

|April 14, 2011

Summary

This summary is machine-generated.

This systematic review examines interventions for infant bronchiolitis, a common respiratory infection. It found 59 studies on treatments, prophylactic measures, and hospital transmission prevention, evaluating their effectiveness and safety.

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Last Updated: Jun 2, 2026

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples

Published on: January 21, 2018

Area of Science:

Pediatrics
Infectious Diseases
Respiratory Medicine

Background:

Bronchiolitis is the most frequent lower respiratory tract infection in infants.
It exhibits a distinct seasonal incidence, peaking in winter or rainy seasons.
Bronchiolitis is a primary cause for pediatric hospitalizations.

Purpose of the Study:

To systematically review the effectiveness of prophylactic interventions for high-risk children with bronchiolitis.
To assess measures for preventing bronchiolitis transmission within hospital settings.
To evaluate the efficacy and safety of various treatments for bronchiolitis.

Main Methods:

A systematic review methodology was employed.
Searches were conducted across major databases (Medline, Embase, Cochrane Library) up to July 2010.
Inclusion criteria encompassed systematic reviews, RCTs, and observational studies; harms alerts were also considered.

Main Results:

A total of 59 relevant studies met the inclusion criteria.
The GRADE system was utilized to evaluate the quality of evidence for interventions.
Data on a wide range of interventions were compiled and analyzed.

Conclusions:

The review synthesizes evidence on the effectiveness and safety of numerous interventions for bronchiolitis.
Interventions discussed include antibiotics, bronchodilators, corticosteroids, and nursing protocols.
The findings provide a comprehensive overview for managing infant bronchiolitis.