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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
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Split liver transplantation: an overview.

S Emre1, V Umman

  • 1Yale University School of Medicine, New Haven, CT, USA. Sukru.emre@yale.edu

Transplantation Proceedings
|April 14, 2011
PubMed
Summary
This summary is machine-generated.

Split liver transplantation (SLT) addresses donor organ shortages by dividing one liver into two grafts. This technique increases organ availability for patients awaiting liver transplantation, especially children.

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Last Updated: Jun 2, 2026

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Area of Science:

  • Hepatobiliary Surgery
  • Transplantation Medicine
  • Surgical Innovation

Background:

  • Liver transplantation (OLT) is the sole treatment for end-stage liver disease, with survival rates reaching 88%-90%.
  • A critical shortage of donor organs leads to approximately 3000 deaths annually in the US among those awaiting OLT.
  • Split liver transplantation (SLT) is a strategy to augment the supply of liver allografts.

Purpose of the Study:

  • To review advancements in split liver transplantation (SLT).
  • To discuss the anatomical and technical aspects of SLT, including ex situ and in situ splitting techniques.
  • To highlight recipient selection criteria crucial for successful SLT outcomes.

Main Methods:

  • Review of current literature on split liver transplantation techniques.
  • Analysis of ex situ (back table) and in situ splitting methods.
  • Discussion of donor selection, surgical expertise, and logistical considerations for SLT.

Main Results:

  • SLT effectively creates two viable grafts from a single donor liver, increasing organ availability.
  • In situ splitting minimizes ischemia time and facilitates inter-center organ sharing.
  • SLT is increasingly adopted as a routine procedure in many transplant centers.

Conclusions:

  • Split liver transplantation is a vital strategy to overcome the liver allograft shortage.
  • Both ex situ and in situ splitting techniques offer distinct advantages for optimizing graft utilization.
  • Successful SLT relies on meticulous donor selection, technical proficiency, and careful recipient matching.