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Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
Living-donor hepatectomy
1Department of Surgery, Ankara University School of Medicine, Ankara, Turkey.
Transplantation Proceedings
|April 14, 2011
Summary
Living-donor hepatectomy is a safe procedure for liver transplantation, offering a vital alternative when deceased donors are unavailable. While effective, the surgery carries inherent risks for the donor who receives no direct medical benefit.
Area of Science:
- Hepatobiliary Surgery
- Transplant Surgery
- Surgical Outcomes
Background:
- Deceased organ donor organ availability is insufficient to meet transplantation demand.
- Living-donor liver transplantation (LDLT) has become a crucial alternative, particularly in regions with donor shortages.
- This study details clinical experience with living-donor hepatectomy procedures.
Purpose of the Study:
- To present the clinical outcomes and experiences with living-donor hepatectomy.
- To evaluate the safety and morbidity associated with donor hepatectomy in LDLT.
Main Methods:
- Retrospective analysis of 140 living donors undergoing hepatectomy between March 2000 and September 2010.
- Data collected included demographics, operation type, operative times, ischemia duration, hospital stay, and complications.
- Surgical procedures included right hepatectomy, left hepatectomy, and left lateral hepatectomy.
Main Results:
- 140 living donors underwent hepatectomy, with 108 right, 17 left, and 15 left lateral procedures.
- No operative or postoperative mortality was observed.
- The overall morbidity rate was 13.57%, with complications including biliary leakages, biliomas, and rare injuries; no reoperations were needed.
Conclusions:
- Living-donor liver transplantation provides a valuable option for patients needing a liver transplant.
- Donor hepatectomy can be performed with a low rate of morbidity.
- The primary drawback remains the surgical risk undertaken by the donor, who does not directly benefit from the procedure.
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