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[Can ventricular dysfunction be prevented or delayed in course?]
1Faculté de médecine Toulouse-Rangueil, Toulouse.
Insights
Preventing symptomatic left ventricular dysfunction is possible by correcting underlying cardiac issues or mitigating harmful neurohormonal responses. Early intervention in myocardial disease can improve patient outcomes.
Area of Science:
- Cardiology
- Heart Failure Research
Abstract:
Left ventricular dysfunction is asymptomatic or paucisymptomatic for a long time. It would be beneficial if progression to the symptomatic stages could be prevented. This is only possible when the abnormal conditions of cardiac load or perfusion which cause the myocardial disease, can be corrected. The treatment of hypertension or valvular disease is an example of this approach. Another approach is to reduce the perverse effects of the neurohormonal adaptations to cardiac failure. The treatment of chronic myocardial infarction by angiotensin converting enzyme inhibitors is an example of this approach.