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Is a benign meningioma always an indolent tumor?

Patricia Menal1, Francisco Javier García-Tirado, Raúl Embún

  • 1Department of Thoracic Surgery, Miguel Servet University Hospital, Paseo Isabel la Católica 1-3, 50009 Saragossa, Spain. p.menal@hotmail.com

Interactive Cardiovascular and Thoracic Surgery
|April 14, 2011
PubMed

Insights

Metastases from benign meningiomas are rare. This case highlights unusual lung and pleural metastases from an undiagnosed meningothelial meningioma, emphasizing the need for vigilance in rare tumor presentations.

Area of Science:

  • Neurosurgery
  • Oncology
  • Pathology

Background:

  • Meningiomas are typically benign, slow-growing tumors originating from the meninges.
  • Metastasis from meningiomas is uncommon, with established patterns of spread.
  • Pulmonary and pleural metastases from meningiomas are exceptionally rare.

Observation:

  • A 58-year-old man presented with a solitary pulmonary nodule.
  • Surgical resection revealed lung metastases.
  • The primary tumor was identified as an undiagnosed meningothelial meningioma.

Findings:

  • This case represents the second reported instance of a meningothelial meningioma with pleural metastases.
  • The patient's outcome was unsatisfactory, indicating aggressive behavior despite benign histology.
  • Metastatic spread to the lungs and pleura from a presumed benign meningioma occurred.

Implications:

  • This case underscores the potential for meningiomas, even histologically benign ones, to metastasize.
  • It highlights the importance of considering meningioma as a differential diagnosis for unexplained pulmonary nodules, especially in patients with a history of meningioma.
  • Further research into the mechanisms of meningioma metastasis is warranted.

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