Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Complex cooperativity in DNA origami revealed via design-dependent defectivity.

Nucleic acids research·2026
Same author

Variable gain DNA nanostructure charge amplifiers for biosensing.

Nanoscale·2024
Same author

DNA Origami Design: A How-To Tutorial.

Journal of research of the National Institute of Standards and Technology·2024
Same author

DNA-PAINT Probe Modifications Support High-Resolution Imaging with Shorter Binding Domains.

ACS nano·2024
Same author

DNA nanostructure decoration: a how-to tutorial.

Nanotechnology·2024
Same author

Binding, brightness, or noise? Extracting temperature-dependent properties of dye bound to DNA.

Biophysical journal·2023
Same journal

Curved interfaces-enhanced oxygen reduction reaction by PtCo alloys anchored MOF-derived carbon.

Nanoscale·2026
Same journal

Broadly neutralizing antibodies against HIV-1 pseudoviruses elicited by envelope trimer DNA with chimeric design delivered <i>via</i> silica-calcium phosphate nanoparticles.

Nanoscale·2026
Same journal

The transition of MXene research: the map and the gap.

Nanoscale·2026
Same journal

Critical interplay of defect engineering and plasmonics in hybrid nanostructures for ultrasensitive photo-enhanced Raman spectroscopy.

Nanoscale·2026
Same journal

Crystallization regulation and electrochemical optimization of free-standing carbon nanofiber-confined vanadium oxide nanodots for advanced flexible zinc ion batteries.

Nanoscale·2026
Same journal

Polariton manipulation <i>via</i> boundary engineering.

Nanoscale·2026
See all related articles

Related Experiment Video

Updated: Jun 2, 2026

Atomically Traceable Nanostructure Fabrication
12:35

Atomically Traceable Nanostructure Fabrication

Published on: July 17, 2015

Lithography, metrology and nanomanufacturing.

J Alexander Liddle1, Gregg M Gallatin

  • 1Center for Nanoscale Science & Technology, National Institute of Standards and Technology, 100 Bureau Drive, Gaithersburg, MD 20899, USA. liddle@nist.gov

Nanoscale
|April 14, 2011
PubMed
Summary
This summary is machine-generated.

Future nanomanufacturing requires inexpensive, real-time metrology for process control. Current top-down semiconductor fabrication relies on expensive metrology, but emerging bottom-up techniques need cost-effective, high-speed measurement solutions.

More Related Videos

Single-Digit Nanometer Electron-Beam Lithography with an Aberration-Corrected Scanning Transmission Electron Microscope
10:25

Single-Digit Nanometer Electron-Beam Lithography with an Aberration-Corrected Scanning Transmission Electron Microscope

Published on: September 14, 2018

Use of Sacrificial Nanoparticles to Remove the Effects of Shot-noise in Contact Holes Fabricated by E-beam Lithography
07:47

Use of Sacrificial Nanoparticles to Remove the Effects of Shot-noise in Contact Holes Fabricated by E-beam Lithography

Published on: February 12, 2017

Related Experiment Videos

Last Updated: Jun 2, 2026

Atomically Traceable Nanostructure Fabrication
12:35

Atomically Traceable Nanostructure Fabrication

Published on: July 17, 2015

Single-Digit Nanometer Electron-Beam Lithography with an Aberration-Corrected Scanning Transmission Electron Microscope
10:25

Single-Digit Nanometer Electron-Beam Lithography with an Aberration-Corrected Scanning Transmission Electron Microscope

Published on: September 14, 2018

Use of Sacrificial Nanoparticles to Remove the Effects of Shot-noise in Contact Holes Fabricated by E-beam Lithography
07:47

Use of Sacrificial Nanoparticles to Remove the Effects of Shot-noise in Contact Holes Fabricated by E-beam Lithography

Published on: February 12, 2017

Area of Science:

  • Nanotechnology and Materials Science
  • Manufacturing Engineering

Background:

  • Semiconductor chip manufacturing, predominantly using top-down lithography, demands high perfection and expensive metrology.
  • Emerging nanomanufacturing techniques, often bottom-up, target lower-cost products and may tolerate less perfection.

Purpose of the Study:

  • To review and compare top-down and bottom-up nanofabrication techniques.
  • To analyze the distinct metrology requirements for different nanomanufacturing approaches.

Main Methods:

  • Review of current top-down lithography for semiconductor fabrication.
  • Analysis of emerging bottom-up nanofabrication methods (e.g., self-assembly, nano-imprint).
  • Comparison of metrology costs and real-time needs for both approaches.

Main Results:

  • Top-down fabrication necessitates costly, often statistical, online metrology due to perfection requirements.
  • Bottom-up techniques, while less perfection-dependent, require cost-effective, real-time online metrology for process control due to inherent variability.

Conclusions:

  • Future nanomanufacturing will likely require "cheap" nanometre-scale metrology operating at high speeds (GHz rates) within the production stream.
  • A shift towards integrated, high-throughput metrology solutions is essential for the economic viability of novel nanomanufacturing processes.