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Updated: Jun 2, 2026

Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation
Published on: August 14, 2017
[Collagen-binding activity of Willebrand factor and thrombocyte aggregation in patients with frostbite]
Abstract:
In the article was quoted data about the thrombocyte aggregation and collagenbinding activity of Willebrand factor in the blood of 50 patients with local frostbite of third and forth degree. Thrombocyte aggregation was studied with the help of photometry. Collagenbinding activity of Willebrand factor was determined with the help of enzyme-linked immunosorbent assay. It was established that decrease of intensity, potential and rate of induced thrombocyte aggregation took place in patients. Collagenbinding activity of Willebrand factor in blood plasma increase in 1, 7-2, 6 times.
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