Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Respiratory Volumes01:15

Respiratory Volumes

Respiratory volumes are crucial metrics, meticulously measured to quantify the air exchanged in and out of the lungs during various phases of the breathing cycle. These precise measurements are vital for assessing lung function, diagnosing respiratory conditions, and monitoring overall respiratory health. Each parameter provides specific insights into the mechanics of breathing and the functional capacity of the lungs.
Tidal Volume (TV) Tidal volume (TV) is the air inhaled or exhaled in a...
Pressure Relationships in Thoracic Cavity01:24

Pressure Relationships in Thoracic Cavity

Breathing, otherwise known as pulmonary ventilation, is the process of air movement into and out of the lungs. The main mechanisms propelling pulmonary ventilation are atmospheric pressure (Patm), intra-pulmonary (Ppul ) or intra-alveolar pressure (Palv) within the alveoli, and intrapleural pressure (Pip) within the pleural cavity.
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs during...
Factors Affecting Pulmonary Ventilation01:19

Factors Affecting Pulmonary Ventilation

Besides the pressure difference between the external environment and the lungs, the airflow rate and ease of pulmonary ventilation are also influenced by three other factors: surface tension of the fluid in the alveoli, compliance of the lungs, and airway resistance.
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Breathing01:05

Breathing

The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
Atelectasis II: Pathophysiology01:10

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
Lung Capacity01:47

Lung Capacity

The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pulmonary blood flow distribution at different lung volumes and body positions.

Scandinavian journal of clinical and laboratory investigation·2011
Same author

Metabolism of [c]-histamine in heart-lung-liver preparations of cats.

British journal of pharmacology and chemotherapy·2008
Same author

Metastatic complications of Staphylococcus aureus septicemia. To seek is to find.

Infection·2000
Same author

Orthostatic hypotension in Alzheimer's disease: result or cause of brain dysfunction?

Aging (Milan, Italy)·1999
Same author

Gly-X-Y repeat sequences in the treatment of active rheumatoid arthritis.

Rheumatology international·1999
Same author

How to interpret differing cerebral blood flow patterns estimated with 99Tcm-HMPAO and 99Tcm-ECD SPET in a healthy population.

Nuclear medicine communications·1999
Same journal

Vitamin K-dependent proteins in patients undergoing head and neck free flap surgery - a prospective observational study.

Scandinavian journal of clinical and laboratory investigation·2026
Same journal

Challenges in the interpretation of amphetamine results: differences of reactivity between immunoassay and immunochromatography.

Scandinavian journal of clinical and laboratory investigation·2026
Same journal

Maternal whole blood mercury, cadmium and lead concentrations during pregnancy and lactation and infant heavy metal status at six months.

Scandinavian journal of clinical and laboratory investigation·2026
Same journal

Performance of Sysmex SP-50 automated slidemakers and stainers in three hematology laboratories.

Scandinavian journal of clinical and laboratory investigation·2026
Same journal

Digital misinformation and parental resistance to newborn heel-prick screening: an Instagram content analysis.

Scandinavian journal of clinical and laboratory investigation·2026
Same journal

Serum Krebs von den Lungen-6 and interstitial lung disease: a brief review.

Scandinavian journal of clinical and laboratory investigation·2026
See all related articles

Related Experiment Video

Updated: Jun 2, 2026

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
12:09

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

Published on: April 19, 2024

Haemodynamic changes at different lung volumes.

M Arborelius1, B Lilja

  • 1Dept. of Clinical Physiology, Malmö General Hospital, Malmö, Sweden.

Scandinavian Journal of Clinical and Laboratory Investigation
|April 15, 2011
PubMed
Summary
This summary is machine-generated.

Pulmonary blood flow distribution (PBFD) and pressures change with lung volume and body position. Higher lung volumes at rest improved PBFD in healthy males, while elevated pressures were observed.

More Related Videos

Combining Volumetric Capnography And Barometric Plethysmography To Measure The Lung Structure-function Relationship
08:25

Combining Volumetric Capnography And Barometric Plethysmography To Measure The Lung Structure-function Relationship

Published on: January 8, 2019

Related Experiment Videos

Last Updated: Jun 2, 2026

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics
12:09

Ex Vivo Porcine Experimental Model for Studying and Teaching Lung Mechanics

Published on: April 19, 2024

Combining Volumetric Capnography And Barometric Plethysmography To Measure The Lung Structure-function Relationship
08:25

Combining Volumetric Capnography And Barometric Plethysmography To Measure The Lung Structure-function Relationship

Published on: January 8, 2019

Area of Science:

  • Physiology
  • Cardiovascular Research
  • Respiratory Physiology

Background:

  • Pulmonary blood flow distribution (PBFD) is influenced by lung volumes and body positions.
  • Understanding these changes is crucial for respiratory and cardiovascular health assessments.

Purpose of the Study:

  • To investigate the effects of varying lung volumes and body positions on PBFD, pulmonary artery pressure (PAP), wedge pressure (Pw), and cardiac output in healthy males.

Main Methods:

  • Measurements of PBFD, PAP, Pw, and cardiac output were performed in 17 healthy males.
  • Data were collected at different lung volumes, including residual volume (RV) and functional residual capacity (FRC), and total lung capacity (TLC).
  • Experiments were conducted in both sitting and lateral body positions.

Main Results:

  • Pulmonary blood flow distribution became more even, and PAP increased at RV compared to FRC in the sitting position.
  • PAP also increased at TLC, but this was associated with more uneven PBFD.
  • In the lateral position, increased PAP at RV resulted in only minor changes to PBFD.

Conclusions:

  • Lung volume and body position significantly affect pulmonary hemodynamics and blood flow distribution.
  • Elevated pressures at RV in erect and lateral positions showed regional differences in pressure augmentation near the diaphragm.