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[Enhancement of cell growth by human interferons]
N Yamaguchi1, L J Tong, Y Yamamura
1Département de Microbiologie, Université Médicale de la Préfecture de Kyoto, Japan.
Comptes Rendus Des Seances De La Societe De Biologie Et De Ses Filiales
|January 1, 1990
Abstract:
The effects of human interferons (HuIFN) on the human osteosarcoma cells were examined. HuIFN-alpha, -beta and -gamma enhanced dose-dependently the cell growth. There was no difference in the degree of the enhancement of the cell growth among HuIFN-alpha, -beta and -gamma. The higher the cell density was, the lower the degree of the enhancement of the cell growth. When HuIFN-gamma was neutralized with anti-HuIFN-gamma, the enhancement of cell growth was not found.