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Updated: Jun 2, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
A cost-effective moderate-intensity interdisciplinary weight-management programme for individuals with prediabetes
1Department of Medicine, Division of Endocrinology, Université de Sherbrooke, Centre de Recherche Clinique Étienne-LeBel, Sherbrooke, Qc J1H 5N4 Quebec, Canada.
An interdisciplinary lifestyle program significantly improved weight and metabolic health in prediabetes patients, preventing type 2 diabetes development. Group seminars alone were ineffective, highlighting the value of personalized intervention for diabetes prevention.
Area of Science:
- Endocrinology and Metabolism
- Preventive Medicine
- Lifestyle Interventions
Background:
- Prediabetes affects a significant portion of the population, increasing the risk of type 2 diabetes.
- Lifestyle modifications are crucial for managing prediabetes and preventing disease progression.
- Identifying effective and cost-efficient interventions is essential for public health.
Purpose of the Study:
- To compare the effectiveness and cost of two distinct lifestyle-modification programs for individuals at high risk of type 2 diabetes.
- To evaluate the impact of an interdisciplinary approach versus group seminars alone on weight, anthropometric measures, and metabolic variables.
Main Methods:
- A randomized controlled trial involving 48 adults with prediabetes and a BMI ≥27 kg/m(2).
- Intervention group received 1-year interdisciplinary counseling with individual sessions and group seminars; control group received seminars only.
- Outcomes measured included weight loss, waist circumference, glucose levels, lipid profiles, and intervention costs.
Main Results:
- The interdisciplinary group achieved significant weight loss (4.9 kg) and waist circumference reduction (5 cm), unlike the group-seminar-only group.
- 50% of the interdisciplinary group lost ≥5% of initial weight, and 27% lost ≥10%, compared to 12% and 4% in the other group.
- Significant improvements in fasting glucose, 2-hour glucose, and lipid profiles were observed in the interdisciplinary group, with no diabetes development, versus 11.5% in the control group. The interdisciplinary approach cost $733.06/year per subject versus $81.36/year for group seminars.
Conclusions:
- A low-cost, moderate-intensity, individual interdisciplinary approach combined with group seminars is effective for significant weight loss and metabolic improvement in prediabetes.
- Group seminars alone are insufficient for achieving meaningful clinical outcomes in this high-risk population.
- This study supports the use of personalized, interdisciplinary lifestyle interventions for effective prediabetes management and type 2 diabetes prevention.
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