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Cognitive and psychosocial development in children with familial hypomagnesaemia

Tulay Guran1, Ayse Arman, Teoman Akcay

  • 1Marmara University, Department of Pediatric Endocrinology and Diabetes, Istanbul, Turkey.

Magnesium Research
|April 15, 2011
PubMed

Insights

Familial hypomagnesaemia (FH) affects children

Area of Science:

  • Pediatric Genetics
  • Neuropsychiatry
  • Child Psychology

Background:

  • Familial hypomagnesaemia (FH) is a rare genetic disorder.
  • While neuromuscular and cardiovascular issues are documented, cognitive and psychosocial development in children with FH is often neglected.

Purpose of the Study:

  • To evaluate the cognitive and psychosocial outcomes in children diagnosed with Familial hypomagnesaemia.
  • To highlight the need for comprehensive neuropsychiatric assessment in managing FH.

Main Methods:

  • Nine children diagnosed with FH underwent psychiatric examinations.
  • Psychometric tests were administered to assess cognitive and psychosocial functioning.
  • Parent-rated Child Behavior Checklist and Child Health Questionnaire were utilized.

Main Results:

  • Participants (median age 10.1 years) exhibited symptoms including hyperactivity, irritability, sleep and speech problems.
  • Common diagnoses included Attention Deficit Hyperactivity Disorder, borderline intelligence, mild mental retardation, and speech disorders.
  • Elevated scores on behavior and health questionnaires indicated compromised psychosocial well-being.

Conclusions:

  • Cognitive and psychosocial deficits significantly impact the morbidity, quality of life, and social performance of children with FH.
  • Routine neuropsychiatric evaluation is crucial for the comprehensive management of pediatric FH cases.
Abstract

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