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Updated: Jun 2, 2026

Co-culture of Living Microbiome with Microengineered Human Intestinal Villi in a Gut-on-a-Chip Microfluidic Device
Published on: August 30, 2016
Community health care: therapeutic opportunities in the human microbiome
Justin L Sonnenburg1, Michael A Fischbach
1Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA. jsonnenburg@stanford.edu
Abstract:
We are never alone. Humans coexist with diverse microbial species that live within and upon us--our so-called microbiota. It is now clear that this microbial community is essentially another organ that plays a fundamental role in human physiology and disease. Basic and translational research efforts have begun to focus on deciphering mechanisms of microbiome function--and learning how to manipulate it to benefit human health. In this Perspective, we discuss therapeutic opportunities in the human microbiome.
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