Related Experiment Video
Updated: Jun 2, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Dimenhydrinate use for children with vomiting.
Paul Enarson1, Serge Gouin, Ran D Goldman
1BC Children's Hospital, Vancouver, BC, Canada.
Dimenhydrinate is generally safe for pediatric use in treating nausea and vomiting. However, physicians should confirm the cause of vomiting and ensure safe medication use to avoid interactions.
Area of Science:
- Pediatric Pharmacology
- Gastroenterology
Background:
- Dimenhydrinate is a common over-the-counter medication for nausea and vomiting in adults.
- Its safety and efficacy in children are not well-established in published literature.
Purpose of the Study:
- To evaluate the safety and potential utility of dimenhydrinate in pediatric patients.
- To address the question of whether this medication is appropriate for use in children.
Main Methods:
- Review of existing literature on dimenhydrinate use in pediatric populations.
- Analysis of reported adverse effects and efficacy data, where available.
Main Results:
- Limited published data exists regarding adverse effects of dimenhydrinate in children.
- Current evidence suggests dimenhydrinate is likely safe for pediatric use.
Conclusions:
- Dimenhydrinate appears to be a safe option for pediatric patients experiencing nausea and vomiting.
- Physicians must diagnose the underlying cause of vomiting before prescribing and ensure safe administration to prevent drug interactions.
Related Concept Videos
Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists
Phenothiazines, such as prochlorperazine...
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
Drug Dosing: Infants and Children
Pathophysiology of Vomiting
Upper Respiratory Drugs: Antitussives, Expectorants, and Mucolytics
Antitussives include codeine, dextromethorphan (Robitussin), and benzonatate (Tessalon). Codeine and dextromethorphan exert their effects centrally by suppressing the cough reflex center in the medulla. Benzonatate operates peripherally within the respiratory tract by anesthetizing...
