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Influence of soy lecithin administration on hypercholesterolemia
Amouni Mohamed Mourad1, Eder de Carvalho Pincinato, Priscila Gava Mazzola
1Department of Pharmacy, Camilo Castelo Branco University, Rua Carolina Fonseca 584-Itaquera, 08230-030 São Paulo, SP, Brazil.
Cholesterol
|April 15, 2011
Summary
Soy lecithin supplementation significantly reduced total cholesterol and LDL cholesterol in hypercholesterolemic patients. Daily intake of soy lecithin may serve as an effective complementary therapy for managing high cholesterol levels.
Area of Science:
- Biochemistry
- Nutrition Science
- Medical Research
Background:
- Cholesterol homeostasis and hepatic lipoprotein metabolism are influenced by dietary lecithin.
- Lecithin's phytotherapeutic properties suggest potential benefits for hypercholesterolemia.
Purpose of the Study:
- To investigate the hypothesis that lecithin administration reduces cholesterol by increasing biliary secretion.
- To evaluate the effect of soy lecithin on total cholesterol and LDL cholesterol in hypercholesterolemic patients.
Main Methods:
- Hypercholesterolemic patients received one 500 mg soy lecithin capsule daily.
- Blood samples were analyzed for total lipids and cholesterol fractions before and after treatment.
- Measurements were taken after one and two months of daily soy lecithin administration.
Main Results:
- Total cholesterol decreased by 40.66% after one month and 42.00% after two months.
- LDL cholesterol decreased by 42.05% after one month and 56.15% after two months.
- Significant reductions were observed within the first month of treatment.
Conclusions:
- Daily soy lecithin administration effectively reduces total cholesterol and LDL cholesterol.
- Soy lecithin shows promise as a supplemental treatment for managing hypercholesterolemia.
- Increased biliary secretion is a potential mechanism for cholesterol reduction.
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