Treatment of obstructive sleep apnoea for chronic cough in children
Laurel Teoh1, Mark Hurwitz, Jason P Acworth
1Department of Paediatrics & Child Health, The Canberra Hospital, PO Box 11, Woden, Canberra, ACT, Australia, 2606.
Insights
No studies show that treating childhood obstructive sleep apnoea (OSA) resolves chronic cough. Further research is needed to determine if OSA therapies help manage cough in children.
Area of Science:
- Pediatric Pulmonology
- Sleep Medicine
- Clinical Research
Background:
- Childhood obstructive sleep apnoea (OSA) involves repeated upper airway obstruction during sleep, disrupting breathing and sleep.
- Chronic cough is a common pediatric issue, and a link with OSA has been suggested by adult studies.
Purpose of the Study:
- To assess if treating OSA effectively resolves chronic cough in children.
- To evaluate the role of OSA treatment in managing pediatric chronic cough.
Main Methods:
- Systematic search of randomized controlled trials (RCTs) in CENTRAL, MEDLINE, and EMBASE databases up to September 2010.
- Inclusion criteria focused on RCTs comparing OSA interventions with control groups in children with chronic cough.
Main Results:
- No eligible randomized controlled trials were identified.
- There is a lack of evidence from RCTs on the efficacy of OSA treatment for chronic cough in children.
Conclusions:
- Currently, no evidence supports using OSA therapies to manage chronic cough in pediatric patients.
- OSA should be managed independently of cough presence; further research is required.
Background:
Childhood obstructive sleep apnoea (OSA) is a disorder that is characterised by repeated episodes of partial or complete upper airway obstruction (UAO) during sleep that result in disruption of normal ventilation and sleep patterns. Chronic cough in children is a significant medical problem and in some situations warrants thorough investigation. There may be an association between chronic cough and OSA as suggested in adult studies.
Objectives:
To evaluate the efficacy of treatment of OSA leading to the resolution of cough in the management of children with chronic cough.
Search Strategy:
We searched the Cochrane Register of Controlled Trials (CENTRAL, The Cochrane Library), MEDLINE and EMBASE. The latest search was performed in September 2010.
Selection Criteria:
All randomised controlled trials comparing an intervention for OSA to a control group (placebo or usual treatment) in children with chronic cough.
Data Collection And Analysis:
We reviewed the search results against the pre-determined criteria for inclusion. Two review authors independently selected the studies. No eligible trials were identified and thus no data were available for analysis.
Main Results:
We found no randomised controlled trials that examined the efficacy of treatment of OSA in the management of children with chronic cough.
Authors' Conclusions:
There is currently no evidence that therapies directed for OSA are useful for the management of chronic cough in children. Until further evidence is available, OSA should be managed on its own merits and the presence or absence of cough should not be used as a decision trigger. Further research examining the effects of this intervention is needed.
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