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Endoscopic anterior approaches and the cerebrospinal fluid (CSF) leak effect: change one thing, change everything

Luigi M Cavallo1, Felice Esposito

  • 1Department of Neurological Sciences, Division of Neurosurgery, Università delgi Studi de Napoli Federico II, Naples, Italy. lcavallo@unina.it

World Neurosurgery
|April 16, 2011
PubMed
Abstract

No abstract available in PubMed .

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Intracranial hypertension is a sustained elevation of intracranial pressure (ICP) above 22 mm Hg. In supine adults, normal ICP is ~7–15 mm Hg.The rigid, nonexpandable cranium contains three components—brain tissue, blood, and cerebrospinal fluid (CSF)—that total ~1,700 mL in a typical adult: 1,400 mL brain (~80%), 150 mL blood (~10%), and 150 mL CSF (~10%). According to the Monro–Kellie doctrine, total intracranial volume is effectively fixed. When one component expands, CSF and venous blood...
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Cerebrospinal fluid (CSF) is a colorless liquid that flows around the brain and the spinal cord, playing a vital role in the protection, support, and overall function of the central nervous system (CNS). CSF production, circulation, and absorption are tightly regulated processes essential for the brain and spinal cord to function properly.
CSF Production
CSF is produced mainly in the choroid plexus, a network of capillaries and ependymal cells located within the ventricular system of the brain.

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