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A Protein Microarray Assay for Serological Determination of Antigen-specific Antibody Responses Following Clostridium difficile Infection
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Diagnosis of botulism types C and D in cattle by a monoclonal antibody-based sandwich ELISA

C E Brooks1, H J Clarke, D A Graham

  • 1Veterinary Sciences Division, Agri-Food and Biosciences Institute Northern Ireland, Stormont, Belfast. cathy.brooks@afbini.gov.uk

The Veterinary Record
|April 16, 2011
PubMed

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Botulism01:22

Botulism

Botulism is a life-threatening neuroparalytic condition caused by botulinum neurotoxin, which is produced by the bacterium Clostridium botulinum, a Gram-positive, spore-forming, obligate anaerobe.In adults, the toxin enters the body in different ways: in foodborne botulism, the preformed toxin is absorbed in the intestine. In wound botulism, spores grow in injured tissue and release the toxin into the blood. Infant botulism differs mechanistically from adult forms. In infants, botulism commonly...
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Western blotting is an analytical technique for protein identification. It has various applications in immunology and medicine, including detecting diseases like bovine spongiform encephalopathy, mad cow disease, and human and feline immunodeficiency virus from biological samples.
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Enzyme-Linked Immunosorbent Assay

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