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Comparative study of two laser Doppler blood flowmeters
N J Barnett1, G Dougherty, S J Pettinger
1School of Engineering, Oxford Polytechnic, Headington, UK.
Journal of Medical Engineering & Technology
|November 1, 1990
Summary
A new infrared laser Doppler blood flow instrument was validated against a gold standard, showing excellent correlation. The wideband mode is recommended for accurate measurements of fast-moving red blood cells.
Area of Science:
- Biomedical Engineering
- Medical Devices
- Physiology
Background:
- Laser Doppler flowmetry is a key technique for non-invasive blood flow measurement.
- Evaluating new instruments is crucial for advancing diagnostic capabilities.
- The Moor MBF3D offers infrared laser Doppler technology with dual-channel capabilities.
Purpose of the Study:
- To evaluate the performance of a new infrared laser Doppler blood flow instrument (Moor MBF3D).
- To compare its measurements with a validated laser Doppler instrument.
- To investigate the impact of processing bandwidth on measurement accuracy.
Main Methods:
- An in vitro model was used to control blood flow velocity and concentration.
- The Moor MBF3D was compared against a Perimed PF3 laser Doppler instrument.
- Different processing bandwidths were tested, including a wideband mode.
Main Results:
- The Moor MBF3D showed high correlation (r=0.96) with the Perimed PF3.
- The wideband mode is recommended for measurements involving fast-moving red blood cells (rbcs).
- Dual-channel operation demonstrated near-identical responses (r=0.999) for simultaneous measurements.
Conclusions:
- The infrared laser Doppler instrument provides reliable blood flow measurements.
- Dual-channel capability allows for simultaneous monitoring of two distinct sites.
- This technology enhances the ability to compare dynamic blood flow responses.