Related Experiment Videos
The effect of BCG-activated macrophages on the B-16 melanoma
C Papilian-Todoruţiu1, R Rişcă, R Mulea
1Department of Experimental Pathology, Oncological Institue, Cluj-Napoca, Romania.
Abstract:
The effects of BCG-activated lund and peritoneal macrophages on the development of the primary tumor and metastases of B-16 melanoma in C57B1 mice have been studied. The BCG-activated macrophages reduced significantly the incidence of metastases in all treated animals and prolonged the mean survival time only in mice with Winn type of neutralization test. The possible mechanisms implied in this biological process are discussed.