Related Experiment Video
Updated: Jun 2, 2026

11:12
Immunometabolic Circuits in Infection for Advancing Host Directed Therapies
Published on: September 13, 2024
EMBO workshop on immunology and metabolism
Bart Staels1, David Dombrowicz, Ursula Grohmann
1INSERM U1011, University of Lille Nord de France and Institut Pasteur de Lille, Lille, France. bart.staels@pasteur-lille.fr
EMBO Reports
|April 16, 2011
Summary
The immune system plays a role in metabolic diseases, and metabolic control impacts immune function. This EMBO workshop explored the intricate connections between immunology and metabolism.
Area of Science:
- Immunology
- Metabolic Science
- Inflammation Research
Background:
- Emerging evidence highlights the immune system's involvement in metabolic diseases.
- Metabolic control is increasingly recognized as crucial for immune system function.
Framework:
- The EMBO Workshop on Immunology & Metabolism convened ~100 scientists in Marseille, France.
- The workshop focused on the interplay between immunological processes and metabolic pathways.
Implementation:
- Discussions centered on recent findings linking immunity and metabolism.
- Exploration of how metabolic states influence immune responses.
Implications:
- Understanding the immunology-metabolism axis is vital for addressing metabolic diseases.
- This interdisciplinary dialogue advances knowledge on inflammation and metabolic health.
Related Concept Videos
Regulation of Metabolism
Cellular needs and conditions vary from cell to cell and change within individual cells over time. For example, the required enzymes and energetic demands of stomach cells are different from those of fat storage cells, skin cells, blood cells, and nerve cells. Furthermore, a digestive cell works much harder to process and break down nutrients during the time that closely follows a meal compared with many hours after a meal. As these cellular demands and conditions vary, so do the amounts and...
Introduction to Metabolism
Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
Development of Immunocompetence
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
Introduction to Lymphatic and Immune System
Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are born...
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are born...
Overview of Metabolism
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Functions of the Lymphatic and Immune System
The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...

