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Peritumoral brain edema in meningiomas : correlation of radiologic and pathologic features

Byung-Won Kim1, Min-Su Kim, Sang-Woo Kim

  • 1Department of Neurosurgery, Yeungnam University College of Medicine, Daegu, Korea.

Journal of Korean Neurosurgical Society
|April 16, 2011
PubMed
Abstract

Insights

Peritumoral brain edema (PTBE) in meningiomas is influenced by tumor characteristics. High signal intensity on T2-weighted MRI is a key predictor of PTBE, aiding in surgical planning.

Area of Science:

  • Neurosurgery
  • Radiology
  • Pathology

Background:

  • Peritumoral brain edema (PTBE) is a common complication in meningiomas.
  • Understanding factors influencing PTBE is crucial for surgical management and patient outcomes.

Purpose of the Study:

  • To retrospectively evaluate radiological and pathological features associated with PTBE in meningiomas.
  • To identify predictive factors for PTBE formation.

Main Methods:

  • Retrospective analysis of 86 meningioma patients' MRI and pathology data.
  • Evaluation of factors: gender, tumor volume, margin shape, arachnoid plane, T2WI signal intensity (SI), WHO grade, and Ki-67 LI.
  • Calculation of edema index (EI) to quantify PTBE.

Main Results:

  • Univariate analysis showed tumor margin shape, arachnoid plane presence, high T2WI SI, and Ki-67 LI were significant predictors of PTBE.
  • Multivariate analysis identified high tumor SI on T2WI as the sole significant independent predictor of PTBE.
  • Tumor volume and gender were not significantly correlated with PTBE.

Conclusions:

  • Irregular tumor margins, absence of arachnoid plane, high T2WI SI, and elevated Ki-67 LI are potential predictors of PTBE in meningiomas.
  • Tumor SI on T2WI is a critical radiological marker for predicting PTBE.
Keywords:
Brain edemaEdema indexIntracranial meningiomaLabeling index

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