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Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Relationship between lower serum cholesterol level and psychiatric disorders.

D Sanyal¹, J Basu, K Banerjee

¹DEBASISH SANYAL, M.B.B.S., Post Graduate Trainee, Department of Psychiatry, Calcutta Medical College, Calcutta.

Indian Journal of Psychiatry

|April 16, 2011

Summary

Male psychiatric patients exhibit lower serum cholesterol levels compared to healthy individuals. This study utilized the General Health Questionnaire (GHQ-60) to assess psychiatric conditions and serum cholesterol in patients.

Keywords:

Cholesterol psychiatric disorders

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Last Updated: Jun 2, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Area of Science:

Psychiatry
Biochemistry
Medical Research

Background:

Psychiatric disorders can influence physiological markers.
Serum cholesterol levels are a key indicator of metabolic and cardiovascular health.
Understanding the interplay between mental health and physical health is crucial for comprehensive patient care.

Purpose of the Study:

To investigate the relationship between psychiatric diagnoses and serum cholesterol levels.
To determine if psychiatric patients exhibit altered serum cholesterol compared to non-psychiatric individuals.
To explore potential gender differences in this relationship.

Main Methods:

Utilized the General Health Questionnaire (GHQ-60) for psychiatric assessment.
Included 50 literate patients aged 15-55 without physical conditions affecting cholesterol.
Contrasted serum cholesterol levels between subjects scoring <11 (no psychiatric disease) and ≥11 (psychiatric diagnosis) on the GHQ.

Main Results:

Male psychiatric patients demonstrated statistically significant lower serum cholesterol levels than normal subjects.
No significant difference in serum cholesterol was observed between female psychiatric patients and normal subjects.
The General Health Questionnaire (GHQ-60) effectively differentiated between psychiatric and non-psychiatric groups.

Conclusions:

Psychiatric diagnosis in males is associated with lower serum cholesterol.
Gender may play a role in the relationship between psychiatric conditions and serum cholesterol.
Further research is warranted to explore the mechanisms underlying these findings.