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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Cross-reactivity00:42

Cross-reactivity

Overview

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Related Experiment Video

Updated: Jun 2, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Novel challenges for the allergist.

Carlo Selmi1

  • 1Department of Medicine, Autoimmunity and Metabolism Unit, IRCCS Istituto Clinico Humanitas, via A. Manzoni 56, 20089, Rozzano, Milan, Italy. carlo.selmi@unimi.it

Clinical Reviews in Allergy & Immunology
|April 16, 2011
PubMed
Summary
This summary is machine-generated.

Recent advances reveal new insights into allergy-related diseases like asthma and eczema. This review covers emerging trends in genomics, epigenetics, and proteomics for understanding these conditions.

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Last Updated: Jun 2, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

Intralymphatic Immunotherapy and Vaccination in Mice
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Published on: February 2, 2014

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E (sIgE)
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Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E (sIgE)

Published on: April 21, 2019

Area of Science:

  • Allergy and immunology research.
  • Investigating respiratory and skin conditions.

Background:

  • Allergy-related diseases such as asthma, eczema, and atopy are increasing.
  • Novel findings are emerging in understanding these conditions.

Discussion:

  • Reviewing current trends in allergy research.
  • Focus on genomics, epigenetics, and proteomics.
  • Critical discussion of new data and its impact.

Key Insights:

  • Genomic data is crucial for understanding allergy.
  • Epigenetic and proteomic factors influence disease development.
  • Interdisciplinary approaches are vital for allergy research.

Outlook:

  • Future research directions in allergy.
  • Potential for novel diagnostic and therapeutic strategies.
  • Integrating multi-omics data for comprehensive insights.