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Updated: Jun 2, 2026
Application of Laparoscopic Hepatectomy Combined with Intraoperative Microwave Ablation in Colorectal Cancer Liver Metastasis
Published on: March 3, 2023
Colorectal liver metastases with extrahepatic disease--a new criteria for oncologic resection?
Terence C Chua1, David L Morris
1Hepatobiliary and Surgical Oncology Unit, UNSW Department of Surgery, St George Hospital and St George Clinical School, University of New South Wales, Kogarah, Sydney, NSW, 2217, Australia. terence.chua@unsw.edu.au
Background:
Emerging data suggest that in the current era of modern systemic therapies, resection of colorectal liver metastases with concomitant extrahepatic disease may be a curative option in selected patients.
Methods:
A commentary of several key recent papers including an international multi-institutional registry study may provide directions in the future management of this disease entity.
Results:
The premise of selecting patients for a surgical approach to resect colorectal liver metastases and concomitant extrahepatic disease should be individualized. Incorporation of key prognostic factors that include the site of extrahepatic disease, the ability to undertake a complete resection, disease responding to chemotherapy, and an assessment of tumor biology through examining an individual's disease history may guide the selection of suitable patients for this therapeutic pursuit. A 5-year survival of 30% may be realized in well-selected patients.
Conclusion:
Concomitant extrahepatic disease in patients with colorectal liver metastases should not be a contraindication to resection of colorectal cancer metastases.
