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Updated: Jun 2, 2026

Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
[Breast cancer in diabetic patients]
Camelia Cristina Cojocaru1, Mihaela Grigore, Ana Cristina Anton
1Universitatea de Medicină şi Farmacie Gr. T. Popa Iaşi, Facultatea de Medicină, Clinica a II(-a) Obstetrică Ginecologie Maternitatea Cuza Vodă Iaşi.
Unlabelled:
Many of the risk factors for postmenopausal breast cancer are related to excess estrogen exposure. Hyperinsulinemia associated with type 2 diabetes mellitus may promote breast cancer via increased peripheral production of estrogens and direct mitogenic effect of insulin itself.
Material And Methods:
Our retro-prospective study compares breast cancer characteristics between two study groups consisting of 53 diabetic and 391 non-diabetic patients diagnosed and treated for breast cancer.
Results:
Almost 12% of the patients presenting breast cancer were diabetic and menopause occurred at 48.71 years for diabetic patients and at 49.87 years for the non-diabetic ones. Type 2 diabetes mellitus patients were treated by diet and oral agents, had greater body mass index (32.18 kg/m2), presented well differentiated (57% in G1) but greater (68% in T2) tumors and an increased incidence of lobular (13%) and mixed type (19%) carcinoma.
Conclusions:
Diet and physical exercises as methods for preventing type 2 diabetes mellitus together with screening strategies among diabetic patients could contribute to decreasing the incidence of breast cancer.
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