[Separation of erythromycin by direct pertraction from simulated broths]
Anca-Irina Galaction1, Nicoleta Nicuţă, D Cascaval
1Facultatea de Bioinginerie Medicală, Catedra de Tehnologie Protetică si Biotehnologii, Universitatea de Medicină si Farmacie Gr.T. Popa Iaşi.
Abstract:
Erythromycin has been separated from simulated broths by free and facilitated pertraction with D2EHPA dissolved in dichloromethane using an U-shaped pertraction cell. The pertraction has been analyzed by means of initial and final mass flows and permeability factor. The main factors which control the pertraction efficiency were identified to be the pH-gradient between the feed and stripping phase, aqueous phases viscosities and mixing intensity.
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