Related Experiment Video
Updated: Jun 2, 2026

Functional Interrogation of Adult Hypothalamic Neurogenesis with Focal Radiological Inhibition
Published on: November 14, 2013
Adult neurogenesis in the hypothalamus: evidence, functions, and implications
Ti-Fei Yuan1, Oscar Arias-Carrión
1Neuroscience, NCI, Shanghai, 200001, China.
Abstract:
Neurogenesis occurs in the adult brain in a constitutive manner under physiological circumstances within two regions: the dentate gyrus of the hippocampus and the subventricular zone of the lateral ventricles. In contrast to these two so-called neurogenic areas, other regions of the brain were considered to be primarily non-neurogenic in nature, implying that no new neurons were formed there under normal conditions. Recently, low proliferative activity was reported in the hypothalamus and the cell layers surrounding the third ventricle. This review summarizes recent evidence for adult neurogenesis in the hypothalamus, and points out the potential contributions of these new neurons to neural processing. We also discussed some technical considerations in investigating neurogenesis in the adult hypothalamus. It is believed that the hypothalamus could serve as a new source and target for stem cell transplantation.
Related Concept Videos
Neurogenesis and Regeneration of Nervous Tissue
Diencephalon: Hypothalamus and Coordination
The hypothalamus interacts with other brain regions, including the pituitary gland, through a direct physical connection called the hypothalamic-pituitary axis. The hypothalamus receives somatic and visceral inputs and...
Diencephalon: Anatomical Regions
Neurotransmitters
Neuroplasticity
Neuron Structure
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to cellular...

