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Related Concept Videos

Antihypertensive Drugs: Vasodilators01:23

Antihypertensive Drugs: Vasodilators

Vasodilators, primarily affecting the smooth muscles within arterial and venous walls, are commonly used for hypertension treatment. Medications such as minoxidil and hydralazine primarily target arteries and arterioles, while sodium nitroprusside acts on arterioles and venules. Minoxidil, functioning as a prodrug, is metabolized by hepatic sulfotransferase into its active form, minoxidil sulfate, after oral administration. This metabolite binds to the sulfonylurea receptor (SUR) component of...

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Related Experiment Video

Updated: Jun 2, 2026

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
06:41

A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis

Published on: March 9, 2015

Monilethrix treated with minoxidil.

A Rossi, A Iorio, E Scali

    International Journal of Immunopathology and Pharmacology
    |April 19, 2011
    PubMed
    Summary
    This summary is machine-generated.

    Topical minoxidil 2% shows promise for treating Monilethrix, a rare hair disorder. This study found it increased normal hair shafts in patients with no adverse effects.

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    Last Updated: Jun 2, 2026

    A New Technique for Quantitative Analysis of Hair Loss in Mice Using Grayscale Analysis
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    Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
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    Published on: January 19, 2024

    Area of Science:

    • Dermatology
    • Trichology

    Background:

    • Monilethrix is a rare genetic hair shaft disorder characterized by fragile, beaded hair.
    • Current treatment options for Monilethrix are limited and often ineffective.

    Observation:

    • Four patients diagnosed with Monilethrix were treated with topical minoxidil 2% solution.
    • The treatment involved applying 1 ml of the solution twice daily for one year.

    Findings:

    • Topical minoxidil 2% significantly increased the diameter of normal hair shafts in all treated patients.
    • No adverse side effects were reported during the one-year treatment period.

    Implications:

    • Topical minoxidil 2% may be a safe and effective therapeutic option for managing Monilethrix.
    • Further research is warranted to confirm these findings in larger patient cohorts.