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Published on: September 27, 2018
Temporary percutaneous and permanent gastric electrical stimulation in children younger than 3 years with chronic
Anders Elfvin1, Gunnar Göthberg2, Hans Lönroth3
1Department of Pediatrics, The Queen Silvia Children's Hospital, Sahlgrenska University Hospital, 416 85 Gothenburg, Sweden.
Insights
Temporary percutaneous gastric electrical stimulation (TPGES) is safe and effective for treating young children with intractable nausea and vomiting. This method helps identify patients who will benefit from permanent gastric electrical stimulation (GES).
Area of Science:
- Pediatric Gastroenterology
- Medical Device Technology
- Clinical Trials
Background:
- Investigating gastric electrical stimulation (GES) for drug-refractory nausea and vomiting in young children.
- Evaluating temporary percutaneous gastric electrical stimulation (TPGES) for pediatric patient selection.
- Reporting on the youngest patients (2-3 years) treated with GES.
Observation:
- Three pediatric patients under 3 years with intractable vomiting underwent TPGES.
- Custom leads were percutaneously implanted under gastroscopic guidance.
- Daily symptom recording during 12-40 days of TPGES.
Findings:
- No technical issues encountered during TPGES procedures.
- All three pediatric patients responded positively to TPGES.
- Patients achieved >50% vomiting reduction with permanent GES.
Implications:
- GES is a viable treatment option for children under 3 with intractable vomiting.
- TPGES is a safe and feasible method for selecting pediatric GES responders.
- This technique allows for extended testing periods to ensure treatment efficacy.
Background:
The aim was to investigate whether young children with drug-refractory nausea and vomiting can be treated with gastric electrical stimulation (GES) in a similar way as adults and to evaluate whether temporary percutaneous gastric electrical stimulation (TPGES) can be used in the pediatric population to select the patients who are responders to GES treatment. We report the clinical results in 3 children between 2 and 3 years of age. To the best of our knowledge, these are the youngest patients treated with GES.
Methods:
Three patients younger than 3 years with intractable vomiting underwent TPGES. Custom-made leads were percutaneously implanted in the gastric wall under gastroscopic guidance. Symptoms were recorded daily during the TPGES stimulation time (12-40 days). Responders were offered permanent GES treatment.
Results:
There were no technical problems. All 3 patients were responders to TPGES. They are now treated with surgically implanted permanent GES and reported greater than 50% vomiting reduction at last visit.
Conclusion:
Children younger than 3 years can be treated with GES in a similar way as adolescents and adults. Temporary percutaneous GES is a safe, feasible technique even in small children, with the possibility to perform the test over several weeks to select responders to GES treatment.
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