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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...

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Updated: Jun 2, 2026

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

Population-based ectopic pregnancy trends, 1993-2007.

Britton Trabert¹, Victoria L Holt, Onchee Yu

¹Department of Epidemiology, University of Washington, Seattle, USA. trabertbl@mail.nih.gov

American Journal of Preventive Medicine

|April 19, 2011

Summary

Ectopic pregnancy rates have been increasing in recent years, highlighting its continued public health significance. Management has shifted towards outpatient and medical treatments over a 15-year period.

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Last Updated: Jun 2, 2026

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Microscopic Cyst Resection for the Treatment of Patients Diagnosed with Epididymal Cyst

Published on: March 31, 2023

Area of Science:

Reproductive Health
Public Health Surveillance
Epidemiology

Background:

Ectopic pregnancy rate accuracy has been historically compromised, hindering public health surveillance.
This impacts the evaluation of ectopic pregnancy's ongoing public health importance.

Purpose of the Study:

To estimate long-term, population-based ectopic pregnancy rates and trends.
To evaluate shifts in outpatient vs. inpatient management.
To assess trends in medical vs. surgical treatment modalities.

Main Methods:

Utilized Group Health Cooperative inpatient and outpatient data from 1993-2007.
Calculated age-adjusted and age-specific ectopic pregnancy rates for women aged 15-44.
Analyzed trends in care setting and treatment modality.

Main Results:

Ectopic pregnancy rates increased from 1993-2004 to 2005-2007 (17.9 to 21.1 per 10,000 woman-years).
Rates per 1000 pregnancies rose from 19.2 to 26.2 (p=0.001).
Shift observed from inpatient to outpatient care and from surgical to medical treatment.

Conclusions:

Ectopic pregnancy rates show an increasing trend over the 15-year study period.
The condition remains a significant public health concern, comparable to previous national estimates.
Management trends indicate a move towards less invasive approaches.