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Updated: Jun 2, 2026

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum
Published on: December 4, 2015
The emerging world of small silencing RNAs in protozoan parasites
Vanessa D Atayde1, Christian Tschudi, Elisabetta Ullu
1Department of Internal Medicine, School of Medicine, Yale University, New Haven, CT 06536, USA.
Abstract:
A new RNA world has emerged in the past 10 years with the discovery of a plethora of 20- to 30-nucleotide long small RNAs that are involved in various gene silencing mechanisms. These small RNAs have considerably changed our view of the regulation of gene expression in eukaryotic organisms, with a major shift towards epigenetic and post-transcriptional mechanisms. In this article, we focus on the striking diversity of small silencing RNAs that have been identified in several protozoan parasites and their potential biological role.
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