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Updated: Jun 2, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
Published on: November 9, 2016
Subcutaneous infusion of fluid in children
1Saint John's Mercy Children's Hospital, St Louis, MO, USA.
Abstract:
In summary, hyaluronidase augmented SCRT is becoming an accepted alternative for children with mild to moderate dehydration when ORT has failed and intravenous access is difficult. While use of a nasogastric tube is an accepted alternative, this technique is invasive and usually requires restraining of the child's extremities and can lead to complications. The use of oral ondansetron has enhanced ORT, but it is not always successful. Hyaluronidase augmented SCRT has provided an additional alternative for parenteral therapy, but knowledge of its indications and expectations for use is required. This article provides the ED nurse with some clinical knowledge of hyaluronidase augmented SCRT and its key differences from IVT (Table). Further study of nursing considerations with this method of parenteral therapy in children is strongly recommended.
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