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Published on: June 13, 2011
Does low serum immunoglobulin level contribute to the origin of a brain abscess?
1Department of Neurosurgery, Faculty Hospital, Olomouc.
Abstract:
Nine patients operated on for a cryptogenic cerebral abscess and healed were studied for serum immunoglobulin levels. There was a control group of another 9 patients operated on in the past for a contusion injury of the brain or cerebral haematoma. All the patients were examined after complete healing, i.e. 6 months after surgery at least. Statistically significant differences in IgA concentrations could be proved for both the groups. There was a statistically significant difference in IgG values as well. No difference was found with IgM. The possible participation of immune mechanisms in the origin of a cryptogenic cerebral abscess is discussed.
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