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Updated: Jun 2, 2026

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
Published on: February 6, 2015
Of timing and surrogates: a way forward for cancer chemoprevention
Patricia A Thompson1, Eugene W Gerner
1Department of Cell and Molecular Medicine, Arizona Cancer Center, and BIO5 Institute, University of Arizona, Tucson,AZ 85724, USA. pthompson@azcc.arizona.edu
Abstract:
Cancer chemoprevention strategies are not widely implemented in clinical practice. Targeting biomarkers in patients with elevated risk of developing cancer by means of short-term administration of certain agents may be a strategy to minimize toxicities while maintaining efficacy in clinical trials that can be completed in years rather than decades.
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