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Related Concept Videos

Jaundice01:25

Jaundice

Jaundice, or icterus, is the yellow discoloration of the skin, sclerae, and mucous membranes. It happens when plasma bilirubin levels rise above 2.5-3 mg/dL, leading to bilirubin deposition in tissue.Bilirubin is a byproduct of hemoglobin degradation. In macrophages, hemoglobin breaks down into globin and heme. Globin is converted into amino acids, while heme is turned into biliverdin by heme oxygenase, which is then reduced to unconjugated bilirubin by biliverdin reductase.Unconjugated...
Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not related to...
Nephrotic Syndrome III : Nursing Management01:24

Nephrotic Syndrome III : Nursing Management

Nursing management for nephrotic syndrome adapts as the disease progresses, with strategies evolving to address advancing symptoms and complications.Early-Stage Management In the early stages, nursing interventions for nephrotic syndrome resemble those used in managing acute glomerulonephritis, focusing on symptom monitoring, fluid balance, and managing mild to moderate edema.Vital Signs: Regularly monitor blood pressure, pulse, respiratory rate, and temperature to promptly identify...
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol abuse, or...
Chronic Kidney Disease IV: Nursing Management01:18

Chronic Kidney Disease IV: Nursing Management

Nursing management is essential for preventing complications, maintaining stability, and improving patients' quality of life in chronic kidney disease (CKD). By using a structured approach, nurses help slow CKD progression and support effective patient care​.1. Comprehensive patient assessmentEffective management begins with nurses reviewing the patient’s medical history, and identifying key risk factors like diabetes, hypertension, and nephrotoxic drug use. Nurses assess signs of fluid...

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Related Experiment Video

Updated: Jun 2, 2026

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma
05:22

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Published on: February 13, 2026

[Managements for jaundice].

Junji Furuse1, Masao Toki, Hiroshi Kitamura

  • 1Division of Medical Oncology, Kyorin University School of Medicine, Japan.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|April 19, 2011
PubMed
Summary
This summary is machine-generated.

Obstructive jaundice, often caused by malignant tumors, requires prompt biliary drainage. Managing complications like cholangitis and bleeding is crucial for patients with advanced cancers and liver failure.

Related Experiment Videos

Last Updated: Jun 2, 2026

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma
05:22

Intraoperative Strategy under Complex Vascular Adhesion for Laparoscopic Radical Resection of Bismuth-Corlette Type IIIb Perihilar Cholangiocarcinoma

Published on: February 13, 2026

Area of Science:

  • Oncology
  • Gastroenterology
  • Hepatology

Context:

  • Jaundice, characterized by yellowing of skin and mucous membranes, results from hyperbilirubinemia.
  • Malignant tumors can cause obstructive jaundice through biliary tract obstruction or liver failure.
  • Hepatic metastases from gastrointestinal malignancies frequently lead to liver failure.

Purpose:

  • To highlight the oncologic emergencies associated with obstructive jaundice.
  • To emphasize the need for timely diagnosis and treatment in advanced hepatic metastases.
  • To discuss complications arising from biliary drainage procedures in obstructive jaundice.

Summary:

  • Obstructive jaundice, linked to cancers like biliary tract and pancreatic head cancer, necessitates biliary drainage for treatment.
  • Complications from biliary drainage, including cholangitis and duodenal ulcers, require urgent management.
  • Advanced hepatic metastases, particularly from gastrointestinal cancers, present limited chemotherapy options and demand rapid therapeutic decisions.

Impact:

  • Improved understanding of obstructive jaundice management in cancer patients.
  • Enhanced recognition of oncologic emergencies related to biliary drainage complications.
  • Facilitation of timely and effective treatment strategies for advanced malignancies causing jaundice.